3BLJ

Crystal structure of human poly(ADP-ribose) polymerase 15, catalytic fragment

3BLJ の概要

• エントリーDOI: 10.2210/pdb3blj/pdb
• 分子名称: Poly(ADP-ribose) polymerase 15, SODIUM ION, CHLORIDE ION, ... (5 entities in total)
• 機能のキーワード: parp, poly(adp-ribose) polymerase, bal-3, sgc, structural genomics consortium, glycosyltransferase, nad, nucleus, transcription, transcription regulation, transferase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus : Q460N3
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 51144.54

構造登録者

Karlberg, T.,Lehtio, L.,Arrowsmith, C.H.,Berglund, H.,Busam, R.D.,Collins, R.,Dahlgren, L.G.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, I.,Kallas, A.,Kotenyova, T.,Moche, M.,Nilsson, M.E.,Nordlund, P.,Nyman, T.,Persson, C.,Sagemark, J.,Svensson, L.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Welin, M.,Weigelt, J.,Structural Genomics Consortium (SGC) (登録日: 2007-12-11, 公開日: 2007-12-25, 最終更新日: 2023-08-30)

• 主引用文献: Karlberg, T.,Klepsch, M.,Thorsell, A.G.,Andersson, C.D.,Linusson, A.,Schuler, H.; Structural Basis for Lack of ADP-ribosyltransferase Activity in Poly(ADP-ribose) Polymerase-13/Zinc Finger Antiviral Protein.; J.Biol.Chem., 290:7336-7344, 2015; PubMed: 25635049; DOI: 10.1074/jbc.M114.630160

実験手法

X-RAY DIFFRACTION (2.2 Å)