3BKB
Crystal structure of human Feline Sarcoma Viral Oncogene Homologue (v-FES)
Summary for 3BKB
Entry DOI | 10.2210/pdb3bkb/pdb |
Descriptor | Proto-oncogene tyrosine-protein kinase Fes/Fps, SULFATE ION, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | fes, v-fes, fujinami, avian sarcoma, viral, oncogene, feline sarcoma virus, sgc, structural genomics consortium, atp-binding, kinase, nucleotide-binding, phosphoprotein, proto-oncogene, sh2 domain, transferase, tyrosine-protein kinase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 44009.31 |
Authors | Filippakopoulos, P.,Salah, E.,Fedorov, O.,Cooper, C.,Ugochukwu, E.,Pike, A.C.W.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2007-12-06, release date: 2007-12-25, Last modification date: 2023-08-30) |
Primary citation | Filippakopoulos, P.,Kofler, M.,Hantschel, O.,Gish, G.D.,Grebien, F.,Salah, E.,Neudecker, P.,Kay, L.E.,Turk, B.E.,Superti-Furga, G.,Pawson, T.,Knapp, S. Structural Coupling of SH2-Kinase Domains Links Fes and Abl Substrate Recognition and Kinase Activation Cell(Cambridge,Mass.), 134:793-803, 2008 Cited by PubMed: 18775312DOI: 10.1016/j.cell.2008.07.047 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.78 Å) |
Structure validation
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