3BJT

Pyruvate kinase M2 is a phosphotyrosine binding protein

Summary for 3BJT

• Entry DOI: 10.2210/pdb3bjt/pdb
• Descriptor: Pyruvate kinase isozymes M1/M2, OXALATE ION, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: pyruvate kinase, acetylation, allosteric enzyme, alternative splicing, glycolysis, magnesium, metal-binding, phosphoprotein, polymorphism, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P14618
• Total number of polymer chains: 4
• Total formula weight: 231895.76

Authors

Wu, N. (deposition date: 2007-12-04, release date: 2008-03-04, Last modification date: 2024-02-21)

• Primary citation: Christofk, H.R.,Vander Heiden, M.G.,Wu, N.,Asara, J.M.,Cantley, L.C.; Pyruvate kinase M2 is a phosphotyrosine-binding protein.; Nature, 452:181-186, 2008; PubMed: 18337815; DOI: 10.1038/nature06667

Experimental method

X-RAY DIFFRACTION (2.5 Å)