3BJF

Pyruvate kinase M2 is a phosphotyrosine binding protein

3BJF の概要

• エントリーDOI: 10.2210/pdb3bjf/pdb
• 分子名称: Pyruvate kinase isozymes M1/M2, 1,6-di-O-phosphono-beta-D-fructofuranose, OXALATE ION, ... (6 entities in total)
• 機能のキーワード: pyruvate kinase, acetylation, allosteric enzyme, alternative splicing, glycolysis, magnesium, metal-binding, phosphoprotein, polymorphism, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 228499.15

構造登録者

Wu, N. (登録日: 2007-12-03, 公開日: 2008-03-04, 最終更新日: 2024-02-21)

• 主引用文献: Christofk, H.R.,Vander Heiden, M.G.,Wu, N.,Asara, J.M.,Cantley, L.C.; Pyruvate kinase M2 is a phosphotyrosine-binding protein.; Nature, 452:181-186, 2008; PubMed: 18337815; DOI: 10.1038/nature06667

実験手法

X-RAY DIFFRACTION (2.03 Å)