3BHE

HIV-1 protease in complex with a three armed pyrrolidine derivative

Summary for 3BHE

• Entry DOI: 10.2210/pdb3bhe/pdb
• Descriptor: Protease, N-({(3R,4R)-4-[(benzyloxy)methyl]pyrrolidin-3-yl}methyl)-N-(2-methylpropyl)benzenesulfonamide (3 entities in total)
• Functional Keywords: protein-ligand complex, hydrolase
• Biological source: Human immunodeficiency virus type 1 (BRU ISOLATE)
• Cellular location: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03367
• Total number of polymer chains: 2
• Total formula weight: 22024.09

Authors

Boettcher, J.,Blum, A.,Heine, A.,Diederich, W.E.,Klebe, G. (deposition date: 2007-11-28, release date: 2008-12-09, Last modification date: 2023-11-01)

• Primary citation: Boettcher, J.,Blum, A.,Heine, A.,Diederich, W.E.,Klebe, G.; HIV-1 protease in complex with a three armed pyrrolidine derivative; To be Published,

Experimental method

X-RAY DIFFRACTION (1.75 Å)