3BHE

HIV-1 protease in complex with a three armed pyrrolidine derivative

3BHE の概要

• エントリーDOI: 10.2210/pdb3bhe/pdb
• 分子名称: Protease, N-({(3R,4R)-4-[(benzyloxy)methyl]pyrrolidin-3-yl}methyl)-N-(2-methylpropyl)benzenesulfonamide (3 entities in total)
• 機能のキーワード: protein-ligand complex, hydrolase
• 由来する生物種: Human immunodeficiency virus type 1 (BRU ISOLATE)
• 細胞内の位置: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03367
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 22024.09

構造登録者

Boettcher, J.,Blum, A.,Heine, A.,Diederich, W.E.,Klebe, G. (登録日: 2007-11-28, 公開日: 2008-12-09, 最終更新日: 2023-11-01)

• 主引用文献: Boettcher, J.,Blum, A.,Heine, A.,Diederich, W.E.,Klebe, G.; HIV-1 protease in complex with a three armed pyrrolidine derivative; To be Published,

実験手法

X-RAY DIFFRACTION (1.75 Å)