3BG9

Crystal Structure of Human Pyruvate Carboxylase (missing the biotin carboxylase domain at the N-terminus) F1077A Mutant

3BG9 の概要

• エントリーDOI: 10.2210/pdb3bg9/pdb
• 関連するPDBエントリー: 1rqh 3BG3 3BG5
• 分子名称: Pyruvate carboxylase, mitochondrial, MANGANESE (II) ION (2 entities in total)
• 機能のキーワード: tim barrel, atp-binding, biotin, disease mutation, gluconeogenesis, ligase, lipid synthesis, manganese, mitochondrion, multifunctional enzyme, nucleotide-binding, phosphoprotein, transit peptide
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Mitochondrion matrix: P11498
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 315100.63

構造登録者

Xiang, S.,Tong, L. (登録日: 2007-11-26, 公開日: 2008-02-26, 最終更新日: 2024-02-21)

• 主引用文献: Xiang, S.,Tong, L.; Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction.; Nat.Struct.Mol.Biol., 15:295-302, 2008; PubMed: 18297087; DOI: 10.1038/nsmb.1393

実験手法

X-RAY DIFFRACTION (3 Å)