3BG4
The crystal structure of guamerin in complex with chymotrypsin and the development of an elastase-specific inhibitor
Summary for 3BG4
Entry DOI | 10.2210/pdb3bg4/pdb |
Descriptor | Chymotrypsin A chain A, Chymotrypsin A chain B, Chymotrypsin A chain C, ... (5 entities in total) |
Functional Keywords | guamerin, chymotrypsin, elastase, inhibitor, digestion, hydrolase, protease, secreted, serine protease, zymogen, protease inhibitor, serine protease inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Hirudo nipponia (Leech) More |
Cellular location | Secreted, extracellular space: P00766 P00766 P00766 Secreted: P46443 |
Total number of polymer chains | 4 |
Total formula weight | 31389.47 |
Authors | Kim, H.,Chu, T.T.T.,Kim, D.Y.,Kim, D.R.,Nguyen, C.M.T.,Choi, J.,Lee, J.R.,Hahn, M.J.,Kim, K.K. (deposition date: 2007-11-26, release date: 2008-07-29, Last modification date: 2023-11-01) |
Primary citation | Kim, H.,Chu, T.T.T.,Kim, D.Y.,Kim, D.R.,Nguyen, C.M.T.,Choi, J.,Lee, J.R.,Hahn, M.J.,Kim, K.K. The crystal structure of guamerin in complex with chymotrypsin and the development of an elastase-specific inhibitor. J.Mol.Biol., 376:184-192, 2008 Cited by PubMed: 18155725DOI: 10.1016/j.jmb.2007.11.089 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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