3BEN

Structure of N-(12-imidazolyl-dodecanoyl)-L-leucine inhibitor bound to the heme domain of Cytochrome P450-BM3

Summary for 3BEN

• Entry DOI: 10.2210/pdb3ben/pdb
• Related: 1BU7 1JPZ
• Descriptor: Cytochrome P450 102, PROTOPORPHYRIN IX CONTAINING FE, N-[12-(1H-imidazol-1-yl)dodecanoyl]-L-leucine, ... (6 entities in total)
• Functional Keywords: protein-substrate complex, hemeprotein, electron transport, fad, flavoprotein, fmn, iron, membrane, metal-binding, monooxygenase, multifunctional enzyme, nadp, oxidoreductase, transport
• Biological source: Bacillus megaterium
• Cellular location: Cytoplasm (By similarity): P14779
• Total number of polymer chains: 2
• Total formula weight: 109553.92

Authors

Tomchick, D.R. (deposition date: 2007-11-19, release date: 2008-09-30, Last modification date: 2023-08-30)

• Primary citation: Haines, D.C.,Chen, B.,Tomchick, D.R.,Bondlela, M.,Hegde, A.,Machius, M.,Peterson, J.A.; Crystal structure of inhibitor-bound P450BM-3 reveals open conformation of substrate access channel.; Biochemistry, 47:3662-3670, 2008; PubMed: 18298086; DOI: 10.1021/bi7023964

Experimental method

X-RAY DIFFRACTION (1.65 Å)