3BEN

Structure of N-(12-imidazolyl-dodecanoyl)-L-leucine inhibitor bound to the heme domain of Cytochrome P450-BM3

3BEN の概要

• エントリーDOI: 10.2210/pdb3ben/pdb
• 関連するPDBエントリー: 1BU7 1JPZ
• 分子名称: Cytochrome P450 102, PROTOPORPHYRIN IX CONTAINING FE, N-[12-(1H-imidazol-1-yl)dodecanoyl]-L-leucine, ... (6 entities in total)
• 機能のキーワード: protein-substrate complex, hemeprotein, electron transport, fad, flavoprotein, fmn, iron, membrane, metal-binding, monooxygenase, multifunctional enzyme, nadp, oxidoreductase, transport
• 由来する生物種: Bacillus megaterium
• 細胞内の位置: Cytoplasm (By similarity): P14779
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 109553.92

構造登録者

Tomchick, D.R. (登録日: 2007-11-19, 公開日: 2008-09-30, 最終更新日: 2023-08-30)

• 主引用文献: Haines, D.C.,Chen, B.,Tomchick, D.R.,Bondlela, M.,Hegde, A.,Machius, M.,Peterson, J.A.; Crystal structure of inhibitor-bound P450BM-3 reveals open conformation of substrate access channel.; Biochemistry, 47:3662-3670, 2008; PubMed: 18298086; DOI: 10.1021/bi7023964

実験手法

X-RAY DIFFRACTION (1.65 Å)