3BAJ

Human Pancreatic Alpha-Amylase in Complex with Nitrate and Acarbose

3BAJ の概要

• エントリーDOI: 10.2210/pdb3baj/pdb
• 関連するPDBエントリー: 1BSI 1CPU 1HNY 2QMK 2QV4 3BAI 3BAK 3BAW 3BAX 3BAY
• 分子名称: Pancreatic alpha-amylase, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACARBOSE DERIVED PENTASACCHARIDE, ... (6 entities in total)
• 機能のキーワード: amylase, anion activation, human, pancreatic, enzyme, hydrolase, acarbose, transglycosylation, chloride, nitrate, carbohydrate metabolism, glycoprotein, glycosidase, metal-binding, pyrrolidone carboxylic acid, secreted
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 57062.34

構造登録者

Fredriksen, J.R.,Maurus, R.,Brayer, G.D. (登録日: 2007-11-07, 公開日: 2008-03-25, 最終更新日: 2023-08-30)

• 主引用文献: Maurus, R.,Begum, A.,Williams, L.K.,Fredriksen, J.R.,Zhang, R.,Withers, S.G.,Brayer, G.D.; Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity; Biochemistry, 47:3332-3344, 2008; PubMed: 18284212; DOI: 10.1021/bi701652t

実験手法

X-RAY DIFFRACTION (2.1 Å)