3B9K

Crystal structure of CD8alpha-beta in complex with YTS 156.7 FAB

3B9K の概要

• エントリーDOI: 10.2210/pdb3b9k/pdb
• 分子名称: Fab Light Chain, Fab Heavy chain, T-cell surface glycoprotein CD8 alpha chain, ... (6 entities in total)
• 機能のキーワード: immunoglobulin domain, v-set, igsf dimer, glycoprotein, immune response, membrane, transmembrane, immune system
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Cell membrane ; Single-pass type I membrane protein : P01731; Membrane ; Single-pass type I membrane protein: P10300
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 150817.30

構造登録者

Shore, D.,Wilson, I.A. (登録日: 2007-11-05, 公開日: 2008-11-11, 最終更新日: 2020-07-29)

• 主引用文献: Shore, D.A.,Issafras, H.,Landais, E.,Teyton, L.,Wilson, I.A.; The Crystal Structure of CD8 in Complex with YTS156.7.7 Fab and Interaction with Other CD8 Antibodies Define the Binding Mode of CD8 alphabeta to MHC Class I; J.Mol.Biol., 384:1190-1202, 2008; PubMed: 18929574; DOI: 10.1016/j.jmb.2008.09.069

実験手法

X-RAY DIFFRACTION (2.7 Å)