3B76

Crystal structure of the third PDZ domain of human ligand-of-numb protein-X (LNX1) in complex with the C-terminal peptide from the coxsackievirus and adenovirus receptor

Summary for 3B76

Related2AWW
DescriptorE3 ubiquitin-protein ligase LNX, SODIUM ION, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordspdz, bound ligand, structural genomics, structural genomics consortium, sgc, ligase, metal-binding, ubl conjugation pathway, zinc-finger, unknown function
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm  Q8TBB1
Total number of polymer chains2
Total molecular weight25796.13
Authors
Primary citation
Ugochukwu, E.,Burgess-Brown, N.,Berridge, G.,Elkins, J.,Bunkoczi, G.,Pike, A.C.W.,Sundstrom, M.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.M.,Gileadi, O.,von Delft, F.,Doyle, D.
Crystal structure of the third PDZ domain of human ligand-of-numb protein-X (LNX1) in complex with the C-terminal peptide from the coxsackievirus and adenovirus receptor.
To be Published,
Experimental method
X-RAY DIFFRACTION (1.75 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.21320.5%0.6%3.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution