3B6E

Crystal structure of human DECH-box RNA Helicase MDA5 (Melanoma differentiation-associated protein 5), DECH-domain

Summary for 3B6E

• Entry DOI: 10.2210/pdb3b6e/pdb
• Descriptor: Interferon-induced helicase C domain-containing protein 1, SODIUM ION (3 entities in total)
• Functional Keywords: dech, dexd/h rna-binding helicase, innate immunity, ifih1, structural genomics, structural genomics consortium, sgc, antiviral defense, atp-binding, diabetes mellitus, host-virus interaction, hydrolase, immune response, nucleotide-binding, nucleus, phosphorylation
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm : Q9BYX4
• Total number of polymer chains: 1
• Total formula weight: 24127.85

Authors

Karlberg, T.,Welin, M.,Arrowsmith, C.H.,Berglund, H.,Busam, R.D.,Collins, R.,Dahlgren, L.G.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, I.,Kallas, A.,Kotenyova, T.,Lehtio, L.,Moche, M.,Nilsson, M.E.,Nordlund, P.,Nyman, T.,Persson, C.,Sagemark, J.,Svensson, L.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Weigelt, J.,Holmberg-Schiavone, L.,Structural Genomics Consortium (SGC) (deposition date: 2007-10-29, release date: 2007-11-13, Last modification date: 2024-02-21)

• Primary citation: Karlberg, T.,Welin, M.,Arrowsmith, C.H.,Berglund, H.,Busam, R.D.,Collins, R.,Dahlgren, L.G.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, I.,Kallas, A.,Kotenyova, T.,Lehtio, L.,Moche, M.,Nilsson, M.E.,Nordlund, P.,Nyman, T.,Persson, C.,Sagemark, J.,Svensson, L.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Weigelt, J.,Holmberg-Schiavone, L.; Human DECH-box RNA Helicase MDA5 (Melanoma differentiation-associated protein 5), DECH-domain.; To be Published,

Experimental method

X-RAY DIFFRACTION (1.6 Å)