3B6E

Crystal structure of human DECH-box RNA Helicase MDA5 (Melanoma differentiation-associated protein 5), DECH-domain

3B6E の概要

• エントリーDOI: 10.2210/pdb3b6e/pdb
• 分子名称: Interferon-induced helicase C domain-containing protein 1, SODIUM ION (3 entities in total)
• 機能のキーワード: dech, dexd/h rna-binding helicase, innate immunity, ifih1, structural genomics, structural genomics consortium, sgc, antiviral defense, atp-binding, diabetes mellitus, host-virus interaction, hydrolase, immune response, nucleotide-binding, nucleus, phosphorylation
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm : Q9BYX4
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 24127.85

構造登録者

Karlberg, T.,Welin, M.,Arrowsmith, C.H.,Berglund, H.,Busam, R.D.,Collins, R.,Dahlgren, L.G.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, I.,Kallas, A.,Kotenyova, T.,Lehtio, L.,Moche, M.,Nilsson, M.E.,Nordlund, P.,Nyman, T.,Persson, C.,Sagemark, J.,Svensson, L.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Weigelt, J.,Holmberg-Schiavone, L.,Structural Genomics Consortium (SGC) (登録日: 2007-10-29, 公開日: 2007-11-13, 最終更新日: 2024-02-21)

• 主引用文献: Karlberg, T.,Welin, M.,Arrowsmith, C.H.,Berglund, H.,Busam, R.D.,Collins, R.,Dahlgren, L.G.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, I.,Kallas, A.,Kotenyova, T.,Lehtio, L.,Moche, M.,Nilsson, M.E.,Nordlund, P.,Nyman, T.,Persson, C.,Sagemark, J.,Svensson, L.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Weigelt, J.,Holmberg-Schiavone, L.; Human DECH-box RNA Helicase MDA5 (Melanoma differentiation-associated protein 5), DECH-domain.; To be Published,

実験手法

X-RAY DIFFRACTION (1.6 Å)