3B6A
Crystal structure of the Streptomyces coelicolor TetR family protein ActR in complex with actinorhodin
Summary for 3B6A
Entry DOI | 10.2210/pdb3b6a/pdb |
Related | 2OPT 3B6C |
Descriptor | ActR protein, 2,2'-[(1R,1'R,3S,3'S)-6,6',9,9'-tetrahydroxy-1,1'-dimethyl-5,5',10,10'-tetraoxo-3,3',4,4',5,5',10,10'-octahydro-1H,1'H-8,8'-bibenzo[g]isochromene-3,3'-diyl]diacetic acid (2 entities in total) |
Functional Keywords | transcriptional repressor, dna-binding protein, tetr family, actinorhodin, ligand, transcription regulation, transcription |
Biological source | Streptomyces coelicolor |
Total number of polymer chains | 8 |
Total formula weight | 206680.76 |
Authors | Willems, A.R.,Junop, M.S. (deposition date: 2007-10-28, release date: 2008-02-05, Last modification date: 2023-08-30) |
Primary citation | Willems, A.R.,Tahlan, K.,Taguchi, T.,Zhang, K.,Lee, Z.Z.,Ichinose, K.,Junop, M.S.,Nodwell, J.R. Crystal structures of the Streptomyces coelicolor TetR-like protein ActR alone and in complex with actinorhodin or the actinorhodin biosynthetic precursor (S)-DNPA. J.Mol.Biol., 376:1377-1387, 2008 Cited by PubMed: 18207163DOI: 10.1016/j.jmb.2007.12.061 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.05 Å) |
Structure validation
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