3B56

Crystal structure of transthyretin in complex with 3,5-diiodosalicylic acid

3B56 の概要

• エントリーDOI: 10.2210/pdb3b56/pdb
• 分子名称: Transthyretin, 2-HYDROXY-3,5-DIIODO-BENZOIC ACID (3 entities in total)
• 機能のキーワード: transthyretin, amyloid inhibitors, iodine, disease mutation, glycoprotein, hormone, polymorphism, polyneuropathy, retinol-binding, secreted, thyroid hormone, transport, vitamin a, transport protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted: P02766
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28334.55

構造登録者

Gales, L.,Damas, A.M. (登録日: 2007-10-25, 公開日: 2008-01-15, 最終更新日: 2023-11-01)

• 主引用文献: Gales, L.,Almeida, M.R.,Arsequell, G.,Valencia, G.,Saraiva, M.J.,Damas, A.M.; Iodination of salicylic acid improves its binding to transthyretin; Biochim.Biophys.Acta, 1784:512-517, 2008; PubMed: 18155178; DOI: 10.1016/j.bbapap.2007.11.014

実験手法

X-RAY DIFFRACTION (1.55 Å)