3AY8

Glutathione S-transferase unclassified 2 from Bombyx mori

3AY8 の概要

• エントリーDOI: 10.2210/pdb3ay8/pdb
• 分子名称: Glutathione S-transferase, GLYCEROL (3 entities in total)
• 機能のキーワード: gst fold, transfer, gst binding, cytosolic, transferase
• 由来する生物種: Bombyx mori (silk moth, silkworm)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 24577.23

構造登録者

Kakuta, Y.,Usuda, K.,Nakashima, T.,Kimura, M.,Aso, Y.,Yamamoto, K. (登録日: 2011-05-02, 公開日: 2011-09-07, 最終更新日: 2023-11-01)

主引用文献

Kakuta, Y.,Usuda, K.,Nakashima, T.,Kimura, M.,Aso, Y.,Yamamoto, K.
Crystallographic survey of active sites of an unclassified glutathione transferase from Bombyx mori
Biochim.Biophys.Acta, 1810:1355-1360, 2011

PubMed Abstract: Glutathione transferase (GST) catalyzes a major step in the xenobiotic detoxification pathway. We previously identified a novel, unclassified GST that is upregulated in an insecticide-resistant silkworm (Bombyx mori) upon insecticide exposure. Here, we sought to further characterize this GST, bmGSTu, by solving and refining its crystal structure and identifying its catalytic residues.

PubMed: 21756974
DOI: 10.1016/j.bbagen.2011.06.022

実験手法

X-RAY DIFFRACTION (2.1 Å)