3AWE

Crystal structure of Pten-like domain of Ci-VSP (248-576)

3AWE の概要

• エントリーDOI: 10.2210/pdb3awe/pdb
• 関連するPDBエントリー: 3AWF 3AWG
• 分子名称: Voltage-sensor containing phosphatase, SULFATE ION, SODIUM ION, ... (5 entities in total)
• 機能のキーワード: ptdins(3, 4, 5)p3, phosphatase, ion channel, hydrolase, membrane protein
• 由来する生物種: Ciona intestinalis (Transparent sea squirt)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 115173.12

構造登録者

Matsuda, M.,Sakata, S.,Takeshita, K.,Suzuki, M.,Yamashita, E.,Okamura, Y.,Nakagawa, A. (登録日: 2011-03-19, 公開日: 2011-05-04, 最終更新日: 2023-11-01)

• 主引用文献: Matsuda, M.,Takeshita, K.,Kurokawa, T.,Sakata, S.,Suzuki, M.,Yamashita, E.,Okamura, Y.,Nakagawa, A.; Crystal structure of the cytoplasmic phosphatase and tensin homolog (PTEN)-like region of Ciona intestinalis voltage-sensing phosphatase provides insight into substrate specificity and redox regulation of the phosphoinositide phosphatase activity; J.Biol.Chem., 286:23368-23377, 2011; PubMed: 21543329; DOI: 10.1074/jbc.M110.214361

実験手法

X-RAY DIFFRACTION (2.77 Å)