3AVP

Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with Pantothenol

Summary for 3AVP

Entry DOI	10.2210/pdb3avp/pdb
Related	3AEZ 3AF0 3AF1 3AF2 3AF3 3AF4 3AVO 3AVQ
Descriptor	Pantothenate kinase, (2S)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide, CITRATE ANION, ... (6 entities in total)
Functional Keywords	homodimer, coa biosynthesis, nucleotide binding, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Mycobacterium tuberculosis
Cellular location	Cytoplasm (Probable): P63810
Total number of polymer chains	1
Total formula weight	37158.21
Authors	Chetnani, B.,Kumar, P.,Abhinav, K.V.,Chhibber, M.,Surolia, A.,Vijayan, M. (deposition date: 2011-03-06, release date: 2011-08-17, Last modification date: 2023-11-01)
Primary citation	Chetnani, B.,Kumar, P.,Abhinav, K.V.,Chhibber, M.,Surolia, A.,Vijayan, M. Location and conformation of pantothenate and its derivatives in Mycobacterium tuberculosis pantothenate kinase: insights into enzyme action Acta Crystallogr.,Sect.D, 67:774-783, 2011 Cited by PubMed: 21904030 DOI: 10.1107/S0907444911024462 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation