3AVP

Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with Pantothenol

3AVP の概要

• エントリーDOI: 10.2210/pdb3avp/pdb
• 関連するPDBエントリー: 3AEZ 3AF0 3AF1 3AF2 3AF3 3AF4 3AVO 3AVQ
• 分子名称: Pantothenate kinase, (2S)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide, CITRATE ANION, ... (6 entities in total)
• 機能のキーワード: homodimer, coa biosynthesis, nucleotide binding, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Mycobacterium tuberculosis
• 細胞内の位置: Cytoplasm (Probable): P63810
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 37158.21

構造登録者

Chetnani, B.,Kumar, P.,Abhinav, K.V.,Chhibber, M.,Surolia, A.,Vijayan, M. (登録日: 2011-03-06, 公開日: 2011-08-17, 最終更新日: 2023-11-01)

• 主引用文献: Chetnani, B.,Kumar, P.,Abhinav, K.V.,Chhibber, M.,Surolia, A.,Vijayan, M.; Location and conformation of pantothenate and its derivatives in Mycobacterium tuberculosis pantothenate kinase: insights into enzyme action; Acta Crystallogr.,Sect.D, 67:774-783, 2011; PubMed: 21904030; DOI: 10.1107/S0907444911024462

実験手法

X-RAY DIFFRACTION (2.6 Å)