3AVK
Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site
Summary for 3AVK
Entry DOI | 10.2210/pdb3avk/pdb |
Related | 3AV9 3AVA 3AVB 3AVC 3AVF 3AVG 3AVH 3AVI 3AVJ 3AVL 3AVM 3AVN |
Related PRD ID | PRD_000824 |
Descriptor | Integrase, LEDGF peptide, SULFATE ION, ... (6 entities in total) |
Functional Keywords | protein-protein interactions, hiv, recombination-inhibitor complex, recombination/inhibitor |
Biological source | Human immunodeficiency virus type 1 (HIV-1) More |
Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12497 |
Total number of polymer chains | 4 |
Total formula weight | 42916.82 |
Authors | Peat, T.S.,Deadman, J.J.,Newman, J.,Rhodes, D.I. (deposition date: 2011-03-05, release date: 2012-01-18, Last modification date: 2013-06-19) |
Primary citation | Rhodes, D.I.,Peat, T.S.,Vandegraaff, N.,Jeevarajah, D.,Newman, J.,Martyn, J.,Coates, J.A.,Ede, N.J.,Rea, P.,Deadman, J.J. Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site. Chembiochem, 12:2311-2315, 2011 Cited by PubMed: 21850718DOI: 10.1002/cbic.201100350 PDB entries with the same primary citation |
Experimental method |
Structure validation
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