3AU8

Crystal structure of the ternary complex of an isomerase

Summary for 3AU8

Entry DOI	10.2210/pdb3au8/pdb
Related	3AU9 3AUA
Descriptor	1-deoxy-D-xylulose 5-phosphate reductoisomerase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, MANGANESE (II) ION, ... (4 entities in total)
Functional Keywords	nadph binding, isomerase
Biological source	Plasmodium falciparum
Cellular location	Plastid, apicoplast: O96693
Total number of polymer chains	2
Total formula weight	113259.94
Authors	Umeda, T.,Tanaka, N.,Kusakabe, Y.,Nakanishi, M.,Kitade, Y.,Nakamura, K.T. (deposition date: 2011-02-01, release date: 2011-08-10, Last modification date: 2023-11-01)
Primary citation	Umeda, T.,Tanaka, N.,Kusakabe, Y.,Nakanishi, M.,Kitade, Y.,Nakamura, K.T. Molecular basis of fosmidomycin's action on the human malaria parasite Plasmodium falciparum Sci Rep, 1:9-9, 2011 Cited by PubMed: 22355528 DOI: 10.1038/srep00009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.86 Å)

Structure validation