3ASJ

Crystal structure of homoisocitrate dehydrogenase in complex with a designed inhibitor

3ASJ の概要

• エントリーDOI: 10.2210/pdb3asj/pdb
• 分子名称: Homoisocitrate dehydrogenase, 3-[(carboxymethyl)sulfanyl]-2-oxopropanoic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total)
• 機能のキーワード: beta-hydroxy acid oxidative decarboxylase, lysine biosynthesis, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• 由来する生物種: Thermus thermophilus
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 146649.11

構造登録者

Nango, E.,Kumasaka, T.,Eguchi, T. (登録日: 2010-12-13, 公開日: 2011-09-21, 最終更新日: 2023-11-01)

• 主引用文献: Nango, E.,Yamamoto, T.,Kumasaka, T.,Eguchi, T.; Structure of Thermus thermophilus homoisocitrate dehydrogenase in complex with a designed inhibitor; J.Biochem., 150:607-614, 2011; PubMed: 21813504; DOI: 10.1093/jb/mvr097

実験手法

X-RAY DIFFRACTION (2.6 Å)