3AHA
Crystal structure of the complex between gp41 fragments N36 and C34 mutant N126K/E137Q
Summary for 3AHA
Entry DOI | 10.2210/pdb3aha/pdb |
Descriptor | Transmembrane protein gp41, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | coiled-coil, viral protein-inhibitor complex, membrane protein |
Biological source | Human immunodeficiency virus 1 (HIV-1) More |
Cellular location | Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: Q70626 |
Total number of polymer chains | 6 |
Total formula weight | 25684.88 |
Authors | Izumi, K.,Nakamura, S.,Nakano, H.,Shimura, K.,Sakagami, Y.,Oishi, S.,Uchiyama, S.,Ohkubo, T.,Kobayashi, Y.,Fujii, N.,Matsuoka, M.,Kodama, E.N. (deposition date: 2010-04-22, release date: 2010-05-19, Last modification date: 2023-11-01) |
Primary citation | Izumi, K.,Nakamura, S.,Nakano, H.,Shimura, K.,Sakagami, Y.,Oishi, S.,Uchiyama, S.,Ohkubo, T.,Kobayashi, Y.,Fujii, N.,Matsuoka, M.,Kodama, E.N. Characterization of HIV-1 resistance to a fusion inhibitor, N36, derived from the gp41 amino terminal heptad repeat. Antiviral Res., 2010 Cited by PubMed: 20438763DOI: 10.1016/j.antiviral.2010.04.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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