3AH3
Crystal structure of LR5-1, 3-isopropylmalate dehydrogenase created by directed evolution
Summary for 3AH3
| Entry DOI | 10.2210/pdb3ah3/pdb |
| Related | 1X0L |
| Descriptor | Homoisocitrate dehydrogenase, SULFATE ION, 1,2-ETHANEDIOL, ... (4 entities in total) |
| Functional Keywords | 3-isopropylmalate dehydrogenase, homoisocitrate dehydrogenase, directed evolution, oxidoreductase |
| Biological source | Thermus thermophilus |
| Total number of polymer chains | 4 |
| Total formula weight | 144516.33 |
| Authors | Tomita, T.,Suzuki, Y.,Kuzuyama, T.,Nishiyama, M. (deposition date: 2010-04-13, release date: 2011-02-02, Last modification date: 2023-11-01) |
| Primary citation | Suzuki, Y.,Asada, K.,Miyazaki, J.,Tomita, T.,Kuzuyama, T.,Nishiyama, M. Enhancement of the latent 3-isopropylmalate dehydrogenase activity of promiscuous homoisocitrate dehydrogenase by directed evolution Biochem.J., 431:401-410, 2010 Cited by PubMed: 20735360DOI: 10.1042/BJ20101246 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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