3AH3

Crystal structure of LR5-1, 3-isopropylmalate dehydrogenase created by directed evolution

3AH3 の概要

• エントリーDOI: 10.2210/pdb3ah3/pdb
• 関連するPDBエントリー: 1X0L
• 分子名称: Homoisocitrate dehydrogenase, SULFATE ION, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: 3-isopropylmalate dehydrogenase, homoisocitrate dehydrogenase, directed evolution, oxidoreductase
• 由来する生物種: Thermus thermophilus
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 144516.33

構造登録者

Tomita, T.,Suzuki, Y.,Kuzuyama, T.,Nishiyama, M. (登録日: 2010-04-13, 公開日: 2011-02-02, 最終更新日: 2023-11-01)

• 主引用文献: Suzuki, Y.,Asada, K.,Miyazaki, J.,Tomita, T.,Kuzuyama, T.,Nishiyama, M.; Enhancement of the latent 3-isopropylmalate dehydrogenase activity of promiscuous homoisocitrate dehydrogenase by directed evolution; Biochem.J., 431:401-410, 2010; PubMed: 20735360; DOI: 10.1042/BJ20101246

実験手法

X-RAY DIFFRACTION (2.4 Å)