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3AE9

Crystal structure of porcine heart mitochondrial complex II bound with N-(3-Pentafluorophenyloxy-phenyl)-2-trifluoromethyl-benzamide

Summary for 3AE9
Entry DOI10.2210/pdb3ae9/pdb
Related3ABV 3AE1 3AE2 3AE3 3AE4 3AE5 3AE6 3AE7 3AE8 3AEA 3AEB 3AEC 3AED 3AEE 3AEF 3AEG
DescriptorSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, PROTOPORPHYRIN IX CONTAINING FE, N-[3-(pentafluorophenoxy)phenyl]-2-(trifluoromethyl)benzamide, ... (12 entities in total)
Functional Keywordsrespiratory complex ii, inhibitors, electron transport, iron, iron-sulfur, metal-binding, mitochondrion, mitochondrion inner membrane, oxidoreductase, transit peptide, transport, tricarboxylic acid cycle, heme, transmembrane, fad-binding protein, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological sourceSus scrofa (Pig)
More
Cellular locationMitochondrion inner membrane ; Peripheral membrane protein ; Matrix side : Q0QF01 Q007T0
Mitochondrion inner membrane ; Multi-pass membrane protein : D0VWV4 A5GZW8
Total number of polymer chains4
Total formula weight126802.78
Authors
Harada, S.,Sasaki, T.,Shindo, M.,Kido, Y.,Inaoka, D.K.,Omori, J.,Osanai, A.,Sakamoto, K.,Mao, J.,Matsuoka, S.,Inoue, M.,Honma, T.,Tanaka, A.,Kita, K. (deposition date: 2010-02-04, release date: 2011-02-09, Last modification date: 2023-11-01)
Primary citationInaoka, D.K.,Shiba, T.,Sato, D.,Balogun, E.O.,Sasaki, T.,Nagahama, M.,Oda, M.,Matsuoka, S.,Ohmori, J.,Honma, T.,Inoue, M.,Kita, K.,Harada, S.
Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
Int J Mol Sci, 16:15287-15308, 2015
Cited by
PubMed: 26198225
DOI: 10.3390/ijms160715287
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.31 Å)
Structure validation

218500

數據於2024-04-17公開中

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