3A8Y

Crystal structure of the complex between the BAG5 BD5 and Hsp70 NBD

3A8Y の概要

• エントリーDOI: 10.2210/pdb3a8y/pdb
• 分子名称: Heat shock 70 kDa protein 1, BAG family molecular chaperone regulator 5, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
• 機能のキーワード: bag domain, hsp70, atpase domain, protein complex, triple helix, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, hydrolase
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm: P08107
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 118886.37

構造登録者

Arakawa, A.,Handa, N.,Ohsawa, N.,Shirouzu, M.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (登録日: 2009-10-13, 公開日: 2010-03-31, 最終更新日: 2023-11-01)

• 主引用文献: Arakawa, A.,Handa, N.,Ohsawa, N.,Shida, M.,Kigawa, T.,Hayashi, F.,Shirouzu, M.,Yokoyama, S.; The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange; Structure, 18:309-319, 2010; PubMed: 20223214; DOI: 10.1016/j.str.2010.01.004

実験手法

X-RAY DIFFRACTION (2.3 Å)