3A8C

Crystal Structure of Trypsin complexed with (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid (soaking with mixture of [(E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid] and [(E)-2-(4-carbamimidoylbenzylideneaminooxy)-2-methylpropanoic acid])

3A8C の概要

• エントリーDOI: 10.2210/pdb3a8c/pdb
• 関連するPDBエントリー: 3A7T 3A7V 3A7W 3A7X 3A7Y 3A7Z 3A80 3A81 3A82 3A83 3A84 3A85 3A86 3A87 3A88 3A89 3A8A 3A8B 3A8D
• 分子名称: Cationic trypsin, CALCIUM ION, (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid, ... (4 entities in total)
• 機能のキーワード: in-crystal chemical ligation, disulfide bond, hydrolase, metal-binding, protease, secreted, serine protease, zymogen
• 由来する生物種: Bos taurus (bovine)
• 細胞内の位置: Secreted, extracellular space: P00760
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 23585.58

構造登録者

Yamane, J.,Yao, M.,Tanaka, I. (登録日: 2009-10-05, 公開日: 2010-09-29, 最終更新日: 2024-10-23)

• 主引用文献: Yamane, J.,Ooyabu, N.,Yao, M.,Takemoto, H.,Tanaka, I.; In-Crystal Chemical Ligation for Drug Discovery; To be Published,

実験手法

X-RAY DIFFRACTION (1.85 Å)