3A79

Crystal structure of TLR2-TLR6-Pam2CSK4 complex

3A79 の概要

• エントリーDOI: 10.2210/pdb3a79/pdb
• 関連するPDBエントリー: 3A7B 3A7C
• 分子名称: Toll-like receptor 2, Variable lymphocyte receptor B, Toll-like receptor 6, Variable lymphocyte receptor B, Pam2CSK4, ... (7 entities in total)
• 機能のキーワード: toll-like receptor, diacyl lipopeptide, innate immunity, leucine rich repeat, cell membrane, cytoplasmic vesicle, disulfide bond, glycoprotein, immune response, inflammatory response, leucine-rich repeat, membrane, receptor, transmembrane, phosphoprotein, immune system
• 由来する生物種: Mus musculus (mouse, Inshore hagfish); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 134737.60

構造登録者

Kang, J.Y.,Jin, M.S.,Lee, J.-O. (登録日: 2009-09-20, 公開日: 2009-11-24, 最終更新日: 2023-11-01)

• 主引用文献: Kang, J.Y.,Nan, X.,Jin, M.S.,Youn, S.-J.,Ryu, Y.H.,Mah, S.,Han, S.H.,Lee, H.,Paik, S.-G.,Lee, J.-O.; Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer; Immunity, 31:873-884, 2009; PubMed: 19931471; DOI: 10.1016/j.immuni.2009.09.018

実験手法

X-RAY DIFFRACTION (2.9 Å)