3A73

Crystal Structure Analysis of Human serum albumin complexed with delta 12-prostaglandin J2

3A73 の概要

• エントリーDOI: 10.2210/pdb3a73/pdb
• 分子名称: Serum albumin, MYRISTIC ACID, (5Z,12Z,15S)-15-hydroxy-11-oxoprosta-5,9,12-trien-1-oic acid, ... (4 entities in total)
• 機能のキーワード: alpha-helical strcture, cleavage on pair of basic residues, disease mutation, disulfide bond, glycation, glycoprotein, lipid-binding, metal-binding, phosphoprotein, secreted, lipid binding protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted: P02768
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 136886.24

構造登録者

Ito, S. (登録日: 2009-09-11, 公開日: 2010-01-19, 最終更新日: 2023-11-01)

• 主引用文献: Yamaguchi, S.,Aldini, G.,Ito, S.,Morishita, N.,Shibata, T.,Vistoli, G.,Carini, M.,Uchida, K.; Delta12-prostaglandin J2 as a product and ligand of human serum albumin: formation of an unusual covalent adduct at His146.; J.Am.Chem.Soc., 132:824-832, 2010; PubMed: 20014793; DOI: 10.1021/ja908878n

実験手法

X-RAY DIFFRACTION (2.19 Å)