3A3E

Crystal structure of penicillin binding protein 4 (dacB) from Haemophilus influenzae, complexed with novel beta-lactam (CMV)

Summary for 3A3E

Entry DOI	10.2210/pdb3a3e/pdb
Related	3A3D 3A3F 3A3I 3A3J
Descriptor	Penicillin-binding protein 4, (2R,4S)-2-[(1R)-1-({(2R)-2-[(4-ethyl-2,3-dioxopiperazin-1-yl)amino]-2-phenylacetyl}amino)-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid (3 entities in total)
Functional Keywords	penicillin binding protein 4, pbp4, dacb, hydrolase
Biological source	Haemophilus influenzae
Total number of polymer chains	2
Total formula weight	100563.01
Authors	Kawai, F.,Roper, D.I.,Park, S.-Y.,Tame, J.R.H. (deposition date: 2009-06-12, release date: 2009-12-22, Last modification date: 2013-11-20)
Primary citation	Kawai, F.,Clarke, T.B.,Roper, D.I.,Han, G.-J.,Hwang, K.Y.,Unzai, S.,Obayashi, E.,Park, S.-Y.,Tame, J.R.H. Crystal structures of penicillin-binding proteins 4 and 5 from Haemophilus influenzae J.Mol.Biol., 396:634-645, 2010 Cited by PubMed: 19958776 DOI: 10.1016/j.jmb.2009.11.055 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation