3ZWO
Crystal structure of ADP ribosyl cyclase complexed with reaction intermediate
Summary for 3ZWO
Entry DOI | 10.2210/pdb3zwo/pdb |
Related | 1LBE 1R0S 1R12 1R15 1R16 3ZWM 3ZWN 3ZWP 3ZWV 3ZWW 3ZWX 3ZWY |
Descriptor | ADP-RIBOSYL CYCLASE, GUANOSINE DIPHOSPHATE RIBOSE, 3-(AMINOCARBONYL)-1-[(2R,3R,4S,5R)-5-({[(S)-{[(S)-{[(2R,3S,4R,5R)-5-(2-AMINO-6-OXO-1,6-DIHYDRO-9H-PURIN-9-YL)-3,4-DIHYD ROXYTETRAHYDROFURAN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]OXY}METHYL)-3,4-DIHYDROXYTETRAHYDROFURAN-2- YL]PYRIDINIUM, ... (4 entities in total) |
Functional Keywords | hydrolase, cd38, hydrolysis, nad, substrate specificity |
Biological source | APLYSIA CALIFORNICA (CALIFORNIA SEA HARE) |
Cellular location | Cytoplasmic vesicle: P29241 |
Total number of polymer chains | 8 |
Total formula weight | 241244.51 |
Authors | Kotaka, M.,Graeff, R.,Zhang, L.H.,Lee, H.C.,Hao, Q. (deposition date: 2011-08-02, release date: 2011-11-30, Last modification date: 2024-10-16) |
Primary citation | Kotaka, M.,Graeff, R.,Chen, Z.,Zhang, L.H.,Lee, H.C.,Hao, Q. Structural Studies of Intermediates Along the Cyclization Pathway of Aplysia Adp-Ribosyl Cyclase. J.Mol.Biol., 415:514-, 2012 Cited by PubMed: 22138343DOI: 10.1016/J.JMB.2011.11.022 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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