3WNR
Multiple binding modes of benzyl isothiocyanate inhibitor complexed with Macrophage Migration Inhibitory Factor
Summary for 3WNR
Entry DOI | 10.2210/pdb3wnr/pdb |
Related | 3WNS 3WNT 4f2k 4OSF |
Descriptor | Macrophage migration inhibitory factor, N-benzylthioformamide, SULFATE ION, ... (6 entities in total) |
Functional Keywords | cytokine, tautomerase, isomerae, benzyl isothiocyante, isomerase-isomerase inhibitor complex, isomerase/isomerase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P14174 |
Total number of polymer chains | 3 |
Total formula weight | 38495.09 |
Authors | Spencer, E.S.,Dale, E.J.,Gommans, A.L.,Rutledge, M.T.,Gamble, A.B.,Smith, R.A.J.,Wilbanks, S.M.,Hampton, M.B.,Tyndall, J.D.A. (deposition date: 2013-12-16, release date: 2014-03-05, Last modification date: 2023-11-08) |
Primary citation | Spencer, E.S.,Dale, E.J.,Gommans, A.L.,Rutledge, M.T.,Vo, C.T.,Nakatani, Y.,Gamble, A.B.,Smith, R.A.,Wilbanks, S.M.,Hampton, M.B.,Tyndall, J.D. Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor Eur.J.Med.Chem., 93:501-510, 2015 Cited by PubMed: 25743213DOI: 10.1016/j.ejmech.2015.02.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.008 Å) |
Structure validation
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