3WNQ
Crystal structure of (R)-carbonyl reductase H49A mutant from Candida Parapsilosis in complex with 2-hydroxyacetophenone
Summary for 3WNQ
Entry DOI | 10.2210/pdb3wnq/pdb |
Descriptor | (R)-specific carbonyl reductase, 2-hydroxy-1-phenylethanone, ZINC ION, ... (4 entities in total) |
Functional Keywords | alcohol dehydrogenase, carbonyl reductase, oxidoreductase |
Biological source | Candida parapsilosis (Yeast) |
Total number of polymer chains | 4 |
Total formula weight | 146185.78 |
Authors | Wang, S.S.,Nie, Y.,Xu, Y.,Zhang, R.Z.,Huang, C.H.,Chan, H.C.,Guo, R.T.,Ko, T.P.,Xiao, R. (deposition date: 2013-12-15, release date: 2014-07-16, Last modification date: 2023-11-08) |
Primary citation | Wang, S.S.,Nie, Y.,Xu, Y.,Zhang, R.Z.,Ko, T.P.,Huang, C.H.,Chan, H.C.,Guo, R.T.,Xiao, R. Unconserved substrate-binding sites direct the stereoselectivity of medium-chain alcohol dehydrogenase Chem.Commun.(Camb.), 50:7770-7772, 2014 Cited by PubMed: 24834985DOI: 10.1039/c4cc01752h PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
Download full validation report