3WKN

Crystal structure of the artificial protein AFFinger p17 (AF.p17) complexed with Fc fragment of human IgG

Summary for 3WKN

• Entry DOI: 10.2210/pdb3wkn/pdb
• Descriptor: Ig gamma-1 chain C region, AFFinger p17, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: immunoglobulin-like beta-sandwich, binding protein, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P01857
• Total number of polymer chains: 16
• Total formula weight: 253785.25

Authors

Watanabe, H.,Honda, S. (deposition date: 2013-10-29, release date: 2014-10-29, Last modification date: 2022-08-24)

• Primary citation: Watanabe, H.,Honda, S.; Adaptive Assembly: Maximizing the Potential of a Given Functional Peptide with a Tailor-Made Protein Scaffold.; Chem.Biol., 22:1165-1173, 2015; PubMed: 26299673; DOI: 10.1016/j.chembiol.2015.07.015

Experimental method

X-RAY DIFFRACTION (2.9 Å)