3WC7
Carboxypeptidase B in complex with EF6265
Summary for 3WC7
| Entry DOI | 10.2210/pdb3wc7/pdb |
| Related | 3WAB 3WC5 3WC6 |
| Descriptor | Carboxypeptidase B, ZINC ION, (2S)-7-amino-2-{[(R)-hydroxy{(1R)-2-methyl-1-[(3-phenylpropanoyl)amino]propyl}phosphoryl]methyl}heptanoic acid, ... (4 entities in total) |
| Functional Keywords | cpb inhibitor, ef6265, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Sus scrofa (Pig) |
| Cellular location | Secreted: P09955 |
| Total number of polymer chains | 1 |
| Total formula weight | 35297.16 |
| Authors | Yoshimoto, N.,Itoh, T.,Inaba, Y.,Yamamoto, K. (deposition date: 2013-05-24, release date: 2013-10-02, Last modification date: 2023-11-08) |
| Primary citation | Yoshimoto, N.,Itoh, T.,Inaba, Y.,Ishii, H.,Yamamoto, K. Structural basis for inhibition of carboxypeptidase B by selenium-containing inhibitor: selenium coordinates to zinc in enzyme. J.Med.Chem., 56:7527-7535, 2013 Cited by PubMed: 24010887DOI: 10.1021/jm400816v PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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