3VXE
Human alpha-thrombin-Bivalirudin complex at PD5.0
Summary for 3VXE
Entry DOI | 10.2210/pdb3vxe/pdb |
Related | 3VXF |
Related PRD ID | PRD_001145 PRD_001148 |
Descriptor | Thrombin light chain, Thrombin heavy chain, BIVALIRUDIN, ... (6 entities in total) |
Functional Keywords | serine protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 36297.27 |
Authors | Yamada, T.,Kurihara, K.,Masumi, K.,Tamada, T.,Tomoyori, K.,Ohnishi, Y.,Tanaka, I.,Kuroki, R.,Niimura, N. (deposition date: 2012-09-12, release date: 2013-09-04, Last modification date: 2023-11-08) |
Primary citation | Yamada, T.,Kurihara, K.,Ohnishi, Y.,Tamada, T.,Tomoyori, K.,Masumi, K.,Tanaka, I.,Kuroki, R.,Niimura, N. Neutron and X-ray crystallographic analysis of the human alpha-thrombin-bivalirudin complex at pD 5.0: protonation states and hydration structure of the enzyme-product complex Biochim.Biophys.Acta, 1834:1532-1538, 2013 Cited by PubMed: 23712263DOI: 10.1016/j.bbapap.2013.05.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
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