3VG0
Antibody Fab fragment
Summary for 3VG0
Entry DOI | 10.2210/pdb3vg0/pdb |
Related | 3v6o |
Descriptor | Monoclonal antibody 9F8 Fab fragment L chain, Monoclonal antibody 9F8 Fab fragment H chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | antibody fab fragment, immunoglobulin fold, n-linked glycosylation site, fab fragment, lbd domain of obr receptor, immune system |
Biological source | Mus musculus More |
Total number of polymer chains | 2 |
Total formula weight | 48406.72 |
Authors | Carpenter, B.,Hemsworth, G.R.,Ross, R.J.,Artymiuk, P.J. (deposition date: 2012-01-10, release date: 2012-03-14, Last modification date: 2023-09-13) |
Primary citation | Carpenter, B.,Hemsworth, G.R.,Wu, Z.,Maamra, M.,Strasburger, C.J.,Ross, R.J.,Artymiuk, P.J. Structure of the human obesity receptor leptin-binding domain reveals the mechanism of leptin antagonism by a monoclonal antibody. Structure, 20:487-497, 2012 Cited by PubMed: 22405007DOI: 10.1016/j.str.2012.01.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.27 Å) |
Structure validation
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