3V8R

Crystal structure of NAD kinase 1 H223E mutant from Listeria monocytogenes in complex with 5'-amino-8-bromo-5'-deoxyadenosine

Summary for 3V8R

Entry DOI	10.2210/pdb3v8r/pdb
Related	2I2C 3V7V 3V7W 3V7Y 3V80 3V8M 3V8N 3V8P 3V8Q
Descriptor	Probable inorganic polyphosphate/ATP-NAD kinase 1, 5'-amino-8-bromo-5'-deoxyadenosine, CITRIC ACID, ... (4 entities in total)
Functional Keywords	ligand-screening by crystallography, two-domain kinase, inorganic polyphosphate/atp-nad kinase 1, transferase
Biological source	Listeria monocytogenes
Total number of polymer chains	1
Total formula weight	31918.67
Authors	Gelin, M.,Poncet-Montange, G.,Assairi, L.,Morellato, L.,Huteau, V.,Dugu, L.,Dussurget, O.,Pochet, S.,Labesse, G. (deposition date: 2011-12-23, release date: 2012-03-14, Last modification date: 2024-02-28)
Primary citation	Gelin, M.,Poncet-Montange, G.,Assairi, L.,Morellato, L.,Huteau, V.,Dugue, L.,Dussurget, O.,Pochet, S.,Labesse, G. Screening and In Situ Synthesis Using Crystals of a NAD Kinase Lead to a Potent Antistaphylococcal Compound. Structure, 20:1107-1117, 2012 Cited by PubMed: 22608967 DOI: 10.1016/j.str.2012.03.024 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.39 Å)

Structure validation