3USN

STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN FIBROBLAST STROMELYSIN-1 INHIBITED WITH THE THIADIAZOLE INHIBITOR IPNU-107859, NMR, 1 STRUCTURE

Summary for 3USN

Entry DOI	10.2210/pdb3usn/pdb
Descriptor	STROMELYSIN-1, ZINC ION, CALCIUM ION, ... (5 entities in total)
Functional Keywords	hydrolase, metalloprotease
Biological source	Homo sapiens (human)
Cellular location	Secreted, extracellular space, extracellular matrix (Probable): P08254
Total number of polymer chains	1
Total formula weight	19475.50
Authors	Stockman, B.J. (deposition date: 1998-06-18, release date: 1999-01-20, Last modification date: 2022-03-16)
Primary citation	Stockman, B.J.,Waldon, D.J.,Gates, J.A.,Scahill, T.A.,Kloosterman, D.A.,Mizsak, S.A.,Jacobsen, E.J.,Belonga, K.L.,Mitchell, M.A.,Mao, B.,Petke, J.D.,Goodman, L.,Powers, E.A.,Ledbetter, S.R.,Kaytes, P.S.,Vogeli, G.,Marshall, V.P.,Petzold, G.L.,Poorman, R.A. Solution structures of stromelysin complexed to thiadiazole inhibitors. Protein Sci., 7:2281-2286, 1998 Cited by PubMed: 9827994 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation