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3UA1

Crystal structure of the cytochrome P4503A4-bromoergocryptine complex

Summary for 3UA1
Entry DOI10.2210/pdb3ua1/pdb
Related1TQN 2JOD 2VOM 3NXU
DescriptorCytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, bromoergocryptine, ... (4 entities in total)
Functional Keywordsprotein-substrate complex, monooxygenase, cytochrome p450 reductase, cytochrome b5, membrane, oxidoreductase
Biological sourceHomo sapiens (human)
Cellular locationEndoplasmic reticulum membrane; Single-pass membrane protein: P08684
Total number of polymer chains1
Total formula weight57028.89
Authors
Sevrioukova, I.F.,Poulos, T.L. (deposition date: 2011-10-20, release date: 2011-12-14, Last modification date: 2023-09-13)
Primary citationSevrioukova, I.F.,Poulos, T.L.
Structural and Mechanistic Insights into the Interaction of Cytochrome P4503A4 with Bromoergocryptine, a Type I Ligand.
J.Biol.Chem., 287:3510-3517, 2012
Cited by
PubMed: 22157006
DOI: 10.1074/jbc.M111.317081
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.15 Å)
Structure validation

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