3T5Z
Crystal structure of the human carbonic anhydrase II in complex with N-methoxy-benzenesulfonamide
Summary for 3T5Z
Entry DOI | 10.2210/pdb3t5z/pdb |
Related | 1CA2 2WEJ 3T5U |
Descriptor | Carbonic anhydrase 2, ZINC ION, N-methoxybenzenesulfonamide, ... (5 entities in total) |
Functional Keywords | protein-inhibitor complex, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29732.19 |
Authors | Di Fiore, A.,Maresca, A.,Alterio, V.,Supuran, C.T.,De Simone, G. (deposition date: 2011-07-28, release date: 2012-06-20, Last modification date: 2023-09-13) |
Primary citation | Di Fiore, A.,Maresca, A.,Alterio, V.,Supuran, C.T.,De Simone, G. Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of N-substituted benzenesulfonamides to human isoform II. Chem.Commun.(Camb.), 47:11636-11638, 2011 Cited by PubMed: 21952494DOI: 10.1039/c1cc14575d PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
Download full validation report