3SVM
Human MPP8 - human DNMT3AK47me2 peptide
Summary for 3SVM
Entry DOI | 10.2210/pdb3svm/pdb |
Related | 3QO2 3SW9 3SWC |
Descriptor | M-phase phosphoprotein 8, DNA (cytosine-5)-methyltransferase 3A (3 entities in total) |
Functional Keywords | epigenetics, methyl-lysine binding, chromodomain, the dimethylated human dnmt3ak47me2 is recognized by the chromodomain of mpp8, mpp8 chromodomain, dimethylated lysine, transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q99549 Q9Y6K1 |
Total number of polymer chains | 2 |
Total formula weight | 9050.29 |
Authors | Chang, Y.,Horton, J.R.,Zhang, X.,Cheng, X. (deposition date: 2011-07-12, release date: 2011-11-30, Last modification date: 2023-09-13) |
Primary citation | Chang, Y.,Sun, L.,Kokura, K.,Horton, J.R.,Fukuda, M.,Espejo, A.,Izumi, V.,Koomen, J.M.,Bedford, M.T.,Zhang, X.,Shinkai, Y.,Fang, J.,Cheng, X. MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a. Nat Commun, 2:533-533, 2011 Cited by PubMed: 22086334DOI: 10.1038/ncomms1549 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.31 Å) |
Structure validation
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