3SVJ
Strep Peptide Deformylase with a time dependent thiazolidine amide
Summary for 3SVJ
Entry DOI | 10.2210/pdb3svj/pdb |
Related | 3STR |
Descriptor | Peptide deformylase 3, SULFATE ION, (4R)-3-(4-[4-(2-chlorophenyl)piperazin-1-yl]-6-{[2-methyl-6-(methylcarbamoyl)phenyl]amino}-1,3,5-triazin-2-yl)-N-methyl-1,3-thiazolidine-4-carboxamide, ... (6 entities in total) |
Functional Keywords | alpha-beta, peptide deformylase, metal binding protein, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Streptococcus pneumoniae |
Total number of polymer chains | 1 |
Total formula weight | 23790.14 |
Authors | Campobasso, N.,Ward, P. (deposition date: 2011-07-12, release date: 2011-07-27, Last modification date: 2014-11-12) |
Primary citation | Totoritis, R.,Duraiswami, C.,Taylor, A.N.,Kerrigan, J.J.,Campobasso, N.,Smith, K.J.,Ward, P.,King, B.W.,Murrayz-Thompson, M.,Jones, A.D.,Van Aller, G.S.,Aubart, K.M.,Zalacain, M.,Thrall, S.H.,Meek, T.D.,Schwartz, B. Understanding the origins of time-dependent inhibition by polypeptide deformylase inhibitors. Biochemistry, 50:6642-6654, 2011 Cited by PubMed: 21711014DOI: 10.1021/bi200655g PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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