3SMN
Crystal structure of human 14-3-3 sigma C38N/N166H in complex with task-3 peptide and stabilizer Fusicoccin A-THF
Summary for 3SMN
Entry DOI | 10.2210/pdb3smn/pdb |
Related | 2O98 3LW1 3MHR |
Descriptor | 14-3-3 protein sigma, TASK-3 peptide, Fusicoccin A-THF, ... (7 entities in total) |
Functional Keywords | helical protein, phosphoprotein, adapter protein, peptide binding protein, nucleus |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P31947 |
Total number of polymer chains | 2 |
Total formula weight | 28213.28 |
Authors | Anders, C.,Schumacher, B.,Ottmann, C. (deposition date: 2011-06-28, release date: 2012-07-11, Last modification date: 2023-09-13) |
Primary citation | Anders, C.,Higuchi, Y.,Koschinsky, K.,Bartel, M.,Schumacher, B.,Thiel, P.,Nitta, H.,Preisig-Muller, R.,Schlichthorl, G.,Renigunta, V.,Ohkanda, J.,Daut, J.,Kato, N.,Ottmann, C. A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem. Biol., 20:583-593, 2013 Cited by PubMed: 23601647DOI: 10.1016/j.chembiol.2013.03.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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