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3SF8

Structural insights into thiol stabilization of DJ-1

Summary for 3SF8
Entry DOI10.2210/pdb3sf8/pdb
DescriptorProtein DJ-1 (3 entities in total)
Functional Keywordsoxidative stress, redox regulation, cysteine oxidation, protecting dj-1 oxidation, reduced dj-1, class i glutamine amidotransferase family, cytoprotective activity against oxidative stress; cysteine sulfenic acid modification, hydrolase, oncoprotein, unknown function
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm: Q99497 Q99497
Total number of polymer chains2
Total formula weight40334.64
Authors
Premkumar, L.,Dobaczewska, M.K.,Riedl, S.J. (deposition date: 2011-06-13, release date: 2011-10-05, Last modification date: 2023-12-06)
Primary citationPremkumar, L.,Dobaczewska, M.K.,Riedl, S.J.
Identification of an artificial peptide motif that binds and stabilizes reduced human DJ-1.
J.Struct.Biol., 176:414-418, 2011
Cited by
PubMed: 21893204
DOI: 10.1016/j.jsb.2011.08.011
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.56 Å)
Structure validation

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