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4LVV

Structure of the THF riboswitch

Replaces:  3SD1
Summary for 4LVV
Entry DOI10.2210/pdb4lvv/pdb
Related3SD3 4LVW 4LVX 4LVY 4LVZ 4LW0
DescriptorTHF riboswitch, N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid (3 entities in total)
Functional Keywordsaptamers, nucleotide, bacterial proteins, base sequence, binding sites, calorimetry, folic acid, gene expression regulation, bacterial, guanine, leucovorin, ligands, magnesium, molecular sequence data, nucleic acid conformation, point mutation, protein binding, s-adenosylmethionine, streptococcus mutans, terminator regions, genetic, tetrahydrofolates, thermodynamics, transcription, three-way junction, pseudoknot, regulation, ncrna, thf binding, mrna, rna
Total number of polymer chains1
Total formula weight29796.02
Authors
Trausch, J.J.,Batey, R.T. (deposition date: 2013-07-26, release date: 2014-03-19, Last modification date: 2024-02-28)
Primary citationTrausch, J.J.,Batey, R.T.
A Disconnect between High-Affinity Binding and Efficient Regulation by Antifolates and Purines in the Tetrahydrofolate Riboswitch.
Chem.Biol., 21:205-216, 2014
Cited by
PubMed: 24388757
DOI: 10.1016/j.chembiol.2013.11.012
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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