3RZ5
Fluoroalkyl and Alkyl Chains Have Similar Hydrophobicities in Binding to the Hydrophobic Wall of Carbonic Anhydrase
Summary for 3RZ5
Entry DOI | 10.2210/pdb3rz5/pdb |
Related | 3RYJ 3RYV 3RYX 3RYY 3RYZ 3RZ0 3RZ1 3RZ7 3RZ8 |
Descriptor | Carbonic anhydrase 2, ZINC ION, N-pentyl-4-sulfamoylbenzamide, ... (5 entities in total) |
Functional Keywords | alpha beta, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29571.75 |
Authors | Snyder, P.W.,Bai, S.,Heroux, A.,Whitesides, G.W. (deposition date: 2011-05-11, release date: 2011-08-10, Last modification date: 2024-02-28) |
Primary citation | Mecinovic, J.,Snyder, P.W.,Mirica, K.A.,Bai, S.,Mack, E.T.,Kwant, R.L.,Moustakas, D.T.,Heroux, A.,Whitesides, G.M. Fluoroalkyl and alkyl chains have similar hydrophobicities in binding to the "hydrophobic wall" of carbonic anhydrase. J.Am.Chem.Soc., 133:14017-14026, 2011 Cited by PubMed: 21790183DOI: 10.1021/ja2045293 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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